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Past Funding Opportunities

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Experimental Human Biology, Winter 2022

The IMA is accepting proposals to address unmet medical needs through human subjects research. Through this solicitation, the IMA seeks to support research projects aimed at testing hypotheses in human subjects that, if validated, have the potential to pave the road to new medicines, vaccines and diagnostics or to enhanced clinical use of existing ones.

Competitive projects will have a strong mechanistic basis or empirical rationale and will utilize the Stanford School of Medicine Clinical and Translational Research Unit (CTRU), where patients can be safely tested and/or treated.

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Molecular Therapeutics, Fall 2021

Identification of medicinally appropriate lead molecules and their subsequent engineering into Drug Prototypes are two major challenges in drug discovery. Through this broad call for proposals, the IMA is soliciting Letters of Intent (LOI) for projects that fall under one of the following modules: High-throughput Screening Assay Development, Small Molecule Drug Prototyping or Prototyping of Protein Therapeutics.

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Vaccine Prototyping using Tonsils-in-a-Dish, Fall 2021

The purpose of this request for proposals (RFP) is to leverage a recent technological advance to prototype new vaccines for infectious and non-infectious diseases. By culturing patient-derived tonsils in a petridish, Stanford researchers have developed a functional lymphoid organotypic systems that recapitulate key features of the human immune system’s germinal center in vitro, including the production of antigen-specific antibodies, somatic hypermutation and affinity maturation, plasmablast differentiation and class-switch recombination (Wagar et al., Nature Med. 27, 125-135, 2021). Such organoids can now be used to engineer new vaccines or assess the efficacy of novel adjuvants.  Through this RFP, the IMA seeks to support meritorious projects targeted at these translational goals. Successful projects will utilize patient derived tonsils-in-a-dish provided by the Stanford Institute for Immunity, Transplantation, and Infection as a model system.

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Cell and Gene Therapies, Summer 2021

In partnership with the Center for Definitive and Curative Medicine (CDCM) and the Center for Cancer Cell Therapy (CCT), the IMA seeks to accelerate the development of promising and innovative early-stage translational stem cell and gene therapies that fill unmet clinical needs.

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Protein Therapeutics Discovery, Winter 2020

Identification of promising lead molecules and their subsequent engineering and development into drug prototypes are two major challenges in molecular therapeutics discovery. The IMA seeks to identify projects that will lead to the discovery of a protein/antibody with sufficiently promising properties to be advanced as a drug prototype.

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COVID-19 Response: Outpatient Studies in Human Subjects, Fall 2020

Through this RFP, IMA seeks to support research projects aimed at testing hypotheses in human subjects that, if validated, have the potential to yield powerful new tools for the modeling, diagnosis, or management of COVID-19 in individuals or populations. 

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Regenerative Therapies for Spinal Muscular Atrophy (SMA), Fall 2020

The goal of this request for proposals is to promote research with the potential to rapidly transform basic and translational regenerative medicine into treatments for SMA.

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COVID-19 Response: Drug and Vaccine Prototyping, Fall 2020

The purpose of this request for proposals (RFP) is to leverage emerging capacity and infrastructure at Stanford to address the current COVID-19 pandemic. Through this RFP, the IMA seeks to support translational research projects that will develop scalable drug screening assays, validate novel drug targets, repurpose molecules with human safety data, or engineer new reagents that will serve as drug or vaccine prototypes for COVID-19.

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High-Throughput Small Molecule Screening, Fall 2020

IMA is accepting proposals for assay development projects to create and optimize miniaturized assays in 384-well microplate format for use in high-throughput, small-molecule screens. Competitive projects will have a strong, novel therapeutic hypothesis and aim to identify small molecule leads for a molecular target or cellular phenotype.  

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Small Molecule Drug Prototyping, Fall 2020

Identification of medicinally appropriate lead molecules and their subsequent engineering into Drug Prototypes are two major challenges in small molecule drug discovery. Through this RFP, the IMA is soliciting Letters of Intent (LOI) for projects that seek to identify new medicinal leads and/or engineer them into Drug Prototypes.

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COVID-19 Response: Drug and Vaccine Prototyping, Spring 2020

The purpose of this request for proposals (RFP) is to leverage emerging capacity and infrastructure at Stanford to address the current COVID-19 pandemic. Through this RFP, the IMA seeks to support translational research projects that will develop scalable drug screening assays, validate novel drug targets, repurpose molecules with human safety data, or engineer new reagents that will serve as drug or vaccine prototypes for COVID-19.

Learn More 


COVID-19 Response: Outpatient Studies in Human Subjects, Spring 2020

Through this RFP, IMA seeks to support research projects aimed at testing hypotheses in human subjects that, if validated, have the potential to yield powerful new tools for the modeling, diagnosis, or management of COVID-19 in individuals or populations. 

Learn More